| West Brom beat Aston Villa 1-0 (A) on 15 Oct 1921 |
| Aston Villa beat Tottenham 2-1 (H) on 1 Oct 1921 |
| Tottenham beat Cardiff 1-0 (A) on 27 Aug 1921 |
| Cardiff beat Middlesbrough 3-1 (H) on 24 Sep 1921 |
| Middlesbrough beat Bradford 2-0 (A) on 8 Oct 1921 |
| Bradford beat Bolton 4-3 (H) on 17 Sep 1921 |
| Bolton beat Huddersfield 3-1 (H) on 24 Sep 1921 |
| Huddersfield beat Newcastle 2-1 (A) on 3 Sep 1921 |
| Newcastle beat Burnley 2-1 (H) on 17 Sep 1921 |
| Burnley beat Sheffield United 2-1 (H) on 8 Oct 1921 |
| Sheffield United beat Arsenal 2-1 (A) on 27 Aug 1921 |
| Arsenal beat Preston North End 1-0 (H) on 5 Sep 1921 |
| Preston North End beat Manchester United 3-2 (H) on 24 Sep 1921 |
| Manchester United beat Everton 2-1 (H) on 3 Sep 1921 |
| Everton beat Birmingham 2-1 (H) on 10 Sep 1921 |
| Birmingham beat Sunderland 1-0 (H) on 1 Oct 1921 |
| Sunderland beat Liverpool 3-0 (H) on 27 Aug 1921 |
| Liverpool beat Chelsea 1-0 (A) on 24 Sep 1921 |
| Chelsea beat Blackburn 1-0 (H) on 3 Sep 1921 |
| Blackburn beat Manchester City 3-1 (H) on 1 Oct 1921 |
| Manchester City beat Oldham 2-1 (H) on 8 Oct 1921 |
| Oldham beat West Brom 1-0 (A) on 24 Sep 1921 |
HWC: Thick arrows show the earliest chain of wins that passes through every team and returns to its start.